This medicine is used to relieve the pain of migraine headaches that are in progress. It will not prevent migraines or reduce the number you may have.

Proper Use

Spray 1 full unit into one nostril. If your headache returns, you may use a second unit at least 2 hours later if your doctor approves. Do not use more than 40 mg of the spray in one day (8 of the 5-mg spray devices or 2 of the 20-mg spray devices).

Please Note

If you have pain or tightness in your chest while using this medicine, tell your doctor. If the chest pain is severe or does not go away, get medical care right away.

If you develop wheezing, heart throbbing, skin lumps or hives, or swelling of your eyelids, face, or lips, call your doctor right away or go to an emergency room.

If you develop feelings of tingling, heat, heaviness, pressure, drowsiness, dizziness, tiredness, or a red face for a short time, contact your doctor for advice.

This nasal spray may make you drowsy or dizzy. Do not drive or operate machinery until you are fully alert.

Females of childbearing age: Do not use this medicine if you are pregnant, think you are pregnant, or plan to become pregnant. Discuss this with your doctor. Also, tell your doctor if you are breast-feeding an infant.

Possible Side Effects

Serious (report these to your doctor right away): Wheezing; heart throbbing; chest pain; chest tightness; skin lumps or hives; swelling of your eyelids, face, or lips.

Other: Drowsiness; dizziness; nausea; feelings of tingling, heat, heaviness, pressure, or tiredness.

Tell your doctor if you have any side effects that continue or get worse.

Possible Drug Interactions

Do not take medicines containing ergotamine (such as Ergomar and Ergostat) or similar drugs (usually used to treat migraine headaches) within 24 hours of a dose of this medicine. Be sure that you tell your doctor if you are taking any other medicines for your migraines, including medicines that are inhaled.

MAO inhibitor antidepressants such as isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate) affect the action of this medicine. Do not take an MAO inhibitor and this medicine within 14 days of each other.

Be sure that you tell all doctors who treat you about all medicines you are taking, including nonprescription products.

This educational document includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Consult your doctor or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.
Other Names For This Medication:

Imitrex Nasal Spray (sumatriptan succinate, nasal); sumatriptan succinate, nasal