Topotecan Hydrochloride, Injection
This medicine is given by IV infusion (slow drip through a needle
into a vein) to treat cancer of the ovaries when other treatment
has failed.
Proper Use
Your doctor or nurse will give you these infusions during each of
the first 5 days of a 21-day period (a treatment course). Four or
more courses of treatment may be necessary. Your doctor may also
prescribe injections of a medicine called growth factor. The
growth factor medicine helps your body replace its white blood
cells, which this medicine (topotecan) destroys. Keep all
appointments for your injections so that your treatment is as
effective and safe as possible.
Please Note
Your doctor will want to test your blood frequently to check on how
this medicine is affecting you. Keep all appointments for blood
tests.
Females of childbearing age: Tell your doctor if you are pregnant
or breast-feeding an infant. Do not receive this medicine if you
are pregnant because it may harm the baby. Do not become pregnant
and do not breast-feed an infant while receiving this medicine.
Possible Side Effects
Serious (report these to your doctor right away): High fever,
severe nausea, vomiting, diarrhea, infection, bruising, bleeding.
Other: Headache, abdominal pain, constipation, loss of hair
(temporary), loss of appetite, muscle or joint pain.
Tell your doctor if you have any side effects that continue or get
worse.
Possible Drug Interactions
When given with this medicine, cisplatin (Platinol) cause side
effects that affects your blood. Talk to your doctor about this.
Be sure that you tell all doctors who treat you about all medicines
you are taking, including nonprescription products.
This educational document includes selected information only and may not
include all side effects of this medicine or interactions with
other medicines. Consult your doctor or pharmacist for more
information or if you have any questions.
Keep all medicines out of the reach of children.
Other Names For This Medication:
Hycamtin (topotecan hydrochloride, injection); topotecan hydrochloride, injection
